Selenium and Cancer: Risk or Protection?
نویسندگان
چکیده
منابع مشابه
Environmental selenium and cancer: risk or protection?
One of the joys of epidemiology is the discovery of a new association that has not been previously reported in the literature. In this issue of Cancer Epidemiology, Biomarkers and Prevention (1), Vinceti et a!. purport to have observed just such an association between malignant melanoma and exposure to selenium in drinking water from a municipal water supply in Reggio Emilia, a municipality in ...
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Some observational studies have shown that elevated serum selenium levels are associated with reduced prostate cancer risk; however, not all published studies support these results. A literature search of PubMed, Embase, Medline, and the Cochrane Library up until September 2016 identified 17 studies suitable for further investigation. A meta-analysis was conducted on these studies to investigat...
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Urothelial bladder cancer is the second most common tumor of the genitourinary tract. In Poland 3,500 new cases of bladder cancer are diagnosed annually. Bladder cancer develops more predominantly in males and increases significantly in incidence between the ages of 60 and 70 years in the life. The risk factors for developing bladder cancer are: cigarette smoking, exposure to aromatic amines, p...
متن کاملSelenium (Se) and breast cancer risk
Material and methods Eight genotypes of 4 most common SNPs localised in GPX1, GPX4, TXNRD2 and SEP15 were selected. Genotyping was performed in 27 triplets matched BRCA1 carriers (cases and controls were matched 1:2) as well as on pairs matched 1:1 consisting of 220 unselected breast cancer (BRCA1 excluded). Cases and controls were matched for year of birth (+/-3 years), number and location of ...
متن کاملFriend or Foe? The Current Epidemiologic Evidence on Selenium and Human Cancer Risk
Scientific opinion on the relationship between selenium and the risk of cancer has undergone radical change over the years, with selenium first viewed as a possible carcinogen in the 1940s then as a possible cancer preventive agent in the 1960s-2000s. More recently, randomized controlled trials have found no effect on cancer risk but suggest possible low-dose dermatologic and endocrine toxicity...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 1995
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/87.7.473